Puzzle Medical Devices® Inc. is developing a percutaneous heart pump for patients with advanced heart failure. The device’s design allows for safe percutaneous implantation to support both renal and cardiac function through a 4 mm-pump implanted in the descending aorta with a 4 Fr axillary driveline, allowing full patient mobility. To date, Puzzle Medical Devices® Inc. has successfully:

• Completed 3 financing rounds in 2022, 2023, and 2025;

• Completed its first-in-human study with all patients experiencing improvements in cardiac and kidney function from 2022 - 2024;

• Grew its team to more than 50 people;

Received U.S. Food and Drug Administration (FDA) Breakthrough Device Designation in 2021.

Here is the link to submit a spontaneous application.